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Inhibition of human endogenous retrovirus-K by antiretroviral drugs

22 Mar 2017

Abstract excerpt

BACKGROUND: Human endogenous retroviruses (HERVs) are genomic sequences of retroviral origin which were believed to be integrated into germline chromosomes millions of years ago and account for nearly 8% of the human genome. Although mostly defective and inactive, some of the HERVs may be activated under certain physiological and pathological conditions. While no drugs are designed specifically targeting HERVs,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28330477
DOI: 10.1186/s12977-017-0347-4

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