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Article

Ginkgo biloba does not alter clearance of flurbiprofen, a cytochrome P450-2C9 substrate.

Journal of clinical pharmacology - 1 Feb 2006

Greenblatt David J, von Moltke Lisa L, Luo Yan, Perloff Elke S, Horan Kelly A, Bruce Allison, Reynolds Robyn C, Harmatz Jerold S, Avula Bharathi, Khan Ikhlas A, Goldman Peter

Abstract excerpt

The effect of Ginkgo biloba on the activity of CYP2C9, the isoform responsible for S-warfarin clearance, was assessed in 11 healthy volunteers who received single 100-mg doses of flurbiprofen, a probe substrate for CYP2C9. Subjects also received either a standardized G biloba leaf preparation (Ginkgold, 3 doses of 120 mg) or matching placebo in a randomized, double-blind, 2-way crossover study. Mean kinetic...

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PMID: 16432273
DOI: 10.1177/0091270005283465

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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