Article
Using population mixtures to optimize the utility of genomic databases: linkage disequilibrium and association study design in India.
Annals of human genetics - 1 Jul 2008
Pemberton T J, Jakobsson M, Conrad D F, Coop G, Wall J D, Pritchard J K, Patel P I, Rosenberg N A
Abstract excerpt
When performing association studies in populations that have not been the focus of large-scale investigations of haplotype variation, it is often helpful to rely on genomic databases in other populations for study design and analysis - such as in the selection of tag SNPs and in the imputation of missing genotypes. One way of improving the use of these databases is to rely on a mixture of database samples that is...
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