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Article

Social interaction-mediated lifespan extension of Drosophila Cu/Zn superoxide dismutase mutants.

Proceedings of the National Academy of Sciences of the United States of America - 27 May 2008

Ruan Hongyu, Wu Chun-Fang

Abstract excerpt

Beneficial effects of social interaction on aging have been studied in humans and other species. We found that short-lived Drosophila mutants of the antioxidant enzyme Cu/Zn superoxide dismutase displayed a robust lifespan extension, with improved stress resistance and motor ability, upon cohousing with active flies of longer lifespan or younger age. Genetic, surgical, and environmental manipulations revealed...

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Identifiers

PMID: 18508973
DOI: 10.1073/pnas.0711127105
PMCID: PMC2396722

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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