Article
P53Arg72 homozygosity and its increased incidence in left-sided sporadic colorectal adenocarcinomas, in a Greek-Caucasian population.
Anticancer research - 1 Jan 2000
Dakouras Anastasios, Nikiteas Nikolaos, Papadakis Emmanuel, Perakis Michael, Valis Dimitrios, Rallis George, Tzanakis Nikolaos, Peros George, Tsigkris Christos, Kittas Christos, Karakitsos Petros
Abstract excerpt
BACKGROUND: The current case-control study was conducted in order to elucidate any possible association of the single nucleotide polymorphism (SNP) of codon 72 of the p53 gene (Arg72Pro) and sporadic colorectal adenocarcinoma development in a Caucasian population in Greece. The distribution of its alleles, in relation to many clinical parameters of the cancer group, was also investigated. MATERIALS AND METHODS:...
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