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Article

Validation of gefitinib effectiveness in a broad panel of head and neck squamous carcinoma cells.

International journal of molecular medicine - 1 Jun 2008

Sebastian S, Azzariti A, Accardi R, Conti D, Pilato B, LaCalamita R, Porcelli L, Simone G M, Tommasi S, Tommasino M, Paradiso A

Abstract excerpt

Recently improved understanding of the pathogenesis of human head and neck squamous cell carcinoma (HNSCC) has led to the development of new, molecular-based therapeutic strategies, one of the more promising is the utilisation of tyrosine kinase (TK) inhibitors, targeting epidermal growth factor receptor (EGFR). In this study, we tested for gefitinib effectiveness in a broad panel of 12 newly established HNSCC...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18506376
DOI: 10.3892/ijmm.21.6.809

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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