Article
Genetic variants of DNA repair gene XPC modulating susceptibility to cervical cancer in North India.
Oncology research - 1 Jan 2010
Gangwar Ruchika, Mittal Balraj, Srivastava Shruti, Singh Hariom, Mittal Rama Devi
Abstract excerpt
The objective of the study was to investigate the association of Xeroderma Pigmentoum group C (XPC) Lys939Gln (A > C) and poly (AT) insertion deletion (PAT -/+) gene polymorphism with the risk of cervical cancer. We enrolled 220 cervical cancer patients and 237 healthy individuals. Polymorphism for XPC gene (Lys939Gln, PAT -/+) was genotyped by polymerase chain reaction and restriction fragment length...
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