Article
Criticality of the biological and physical stimuli array inducing resident cardiac stem cell determination.
Stem cells (Dayton, Ohio) - 1 Aug 2008
Forte Giancarlo, Carotenuto Felicia, Pagliari Francesca, Pagliari Stefania, Cossa Paolo, Fiaccavento Roberta, Ahluwalia Arti, Vozzi Giovanni, Vinci Bruna, Serafino Annalucia, Rinaldi Antonio, Traversa Enrico, Carosella Luciana, Minieri Marilena, Di Nardo Paolo
Abstract excerpt
The replacement of injured cardiac contractile cells with stem cell-derived functionally efficient cardiomyocytes has been envisaged as the resolutive treatment for degenerative heart diseases. Nevertheless, many technical issues concerning the optimal procedures to differentiate and engraft stem cells remain to be answered before heart cell therapy could be routinely used in clinical practice. So far, most...
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