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Article

Structure of Escherichia coli tyrosine kinase Etk reveals a novel activation mechanism.

The EMBO journal - 18 Jun 2008

Lee Daniel C, Zheng Jimin, She Yi-Min, Jia Zongchao

Abstract excerpt

While protein tyrosine (Tyr) kinases (PTKs) have been extensively characterized in eukaryotes, far less is known about their emerging counterparts in prokaryotes. The inner-membrane Wzc/Etk protein belongs to the bacterial PTK family, which has an important function in regulating the polymerization and transport of virulence-determining capsular polysaccharide (CPS). The kinase uses a unique two-step activation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18497741
DOI: 10.1038/emboj.2008.97
PMCID: PMC2435132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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