Article
Comparative analysis of monoamine oxidase intronic polymorphisms in primates.
Gene - 15 Jul 2008
Hong Kyung-Won, Hayasaka Ikuo, Murayama Yuichi, Ito Shin'ichi, Inoue-Murayama Miho
Abstract excerpt
Monoamine oxidases (MAOs) are involved in the degradation of various biogenic amines such as dopamine and serotonin. Two isozymic genes, MAOA and MAOB, have been identified, both of which are located on the X chromosome. In humans, intron 2 of both MAOs contains dinucleotide repeats, MAin2 and MBin2, that have been suggested as candidate genes for mood disorders and Parkinson's disease. In this study, we surveyed...
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