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Leishmania majorAbrogates Gamma Interferon-Induced Gene Expression in Human Macrophages from a Global Perspective

1 May 2007

Abstract excerpt

Infection with Leishmania major triggers several pathways in the host cell that are crucial to initial infection as well as those that are used by Leishmania to enhance its replication and virulence. To identify the molecular events of the host cell in response to Leishmania, the global gene expression of the human monocytic cell line THP-1 either infected with Leishmania major in the presence and absence of...

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PMID: 17470541
DOI: 10.1128/iai.00277-07

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