Article
Interleukin-12 receptor beta1 polymorphisms and nontuberculous mycobacterial lung diseases.
Lung - 1 Jan 2000
Park Hye Yun, Kwon Yong Soo, Ki Chang-Seok, Suh Gee Young, Chung Man Pyo, Kim Hojoong, Kwon O Jung, Koh Won-Jung
Abstract excerpt
The pathway involving interferon-gamma and interleukin (IL)-12 plays an important role in host defense against mycobacterial infections. Recent studies have indicated that IL-12 receptor beta1 (IL-12Rbeta1) gene polymorphisms are associated with susceptibility to pulmonary tuberculosis. However, there have been no reports of an association between IL-12Rbeta1 gene polymorphism and lung disease caused by...
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