Article
An accurate model for genetic hitchhiking.
Genetics - 1 Jan 2008
Eriksson Anders, Fernström Pontus, Mehlig Bernhard, Sagitov Serik
Abstract excerpt
We suggest a simple deterministic approximation for the growth of the favored-allele frequency during a selective sweep. Using this approximation we introduce an accurate model for genetic hitchhiking. Only when Ns<10 (N is the population size and s denotes the selection coefficient) are discrepancies between our approximation and direct numerical simulations of a Moran model notable. Our model describes the gene...
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