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Article

Disruption of ubiquitin-mediated processes in diseases of the brain and bone.

Biochemical Society transactions - 1 Jun 2008

Layfield Robert, Searle Mark S

Abstract excerpt

A role for ubiquitin in the pathogenesis of human diseases was first suggested some two decades ago, from studies that localized the protein to intracellular protein aggregates, which are a feature of the major human neurodegenerative disorders. Although several different mechanisms have been pro...

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Source

Identifiers

PMID: 18481983
DOI: 10.1042/BST0360469

Genes

SQSTM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18481983-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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