Article
A position-effect assay for boundaries of higher order chromosomal domains.
Cell - 8 Mar 1991
Kellum R, Schedl P
Abstract excerpt
Eukaryotic chromosomes are thought to be organized into a series of discrete higher order chromatin domains. This organization is believed to be important not only in the compaction of the chromatin fiber, but also in the utilization of genetic information. Each domain would define an independent unit of gene activity, insulated from the regulatory influences of adjacent domains. Critical to this model of...
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