Article
Genetic polymorphisms of the RAS-cytokine pathway and chronic kidney disease.
Pediatric nephrology (Berlin, Germany) - 1 Jul 2008
Wong Craig, Kanetsky Peter, Raj Dominic
Abstract excerpt
Chronic kidney disease (CKD) in children is irreversible. It is associated with renal failure progression and atherosclerotic cardiovascular (CV) abnormalities. Nearly 60% of children with CKD are affected since birth with congenital or inherited kidney disorders. Preliminary evidence primarily from adult CKD studies indicates common genetic risk factors for CKD and atherosclerotic CV disease. Although multiple...
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