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Article

IL-12 RB1 genetic variants contribute to human susceptibility to severe acute respiratory syndrome infection among Chinese.

PloS one - 14 May 2008

Tang Fang, Liu Wei, Zhang Fang, Xin Zhong-Tao, Wei Mao-Ti, Zhang Pan-He, Yang Hong, Ly Hinh, Cao Wu-Chun

Abstract excerpt

BACKGROUND: Cytokines play important roles in antiviral action. We examined whether polymorphisms of interleukin (IL)-12 receptor B1 (IL-12RB1) affect the susceptibility to and outcome of severe acute respiratory syndrome (SARS). METHODS: A case-control study was carried out in Chinese SARS patients and healthy controls. The genotypes of 4SNPs on IL-12 RB1 gene, +705A/G,+1158T/C, +1196G/C and +1664 C/T, were...

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Identifiers

PMID: 18478121
DOI: 10.1371/journal.pone.0002183
PMCID: PMC2367437

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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