Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dissection of Signal Transduction Pathways as a Tool for the Development of Targeted Therapies of Hepatocellular Carcinoma

1 Sept 2007

Abstract excerpt

Genomic instability during hepatocarcinogenesis causes changes in signal transduction network. Strategies for identification of new markers/therapeutic targets include discovery of early molecular changes during hepatocarcinogenesis, relevant to preneoplastic lesions progression to full malignancy in rodent models, and evaluation of these changes in human hepatocellular carcinomas (HCCs). Activation of ERB...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Cancer-related Molecular Pathways
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18474008
DOI: 10.2174/157488707781662715

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dissection of Signal Transduction Pathways as a Tool for the Development of Targeted Therapies of Hepatocellular CarcinomaPMID 18474008Read ↗

Molecular Mechanisms in Tumorigenesis of Hepatocellular Carcinoma and in Target Treatments—An OverviewSemantic proximity Read ↗

Molecular Pathways and Related Target Therapies in Liver CarcinomaSemantic proximity Read ↗

Involvement of DNA Damage Response Pathways in Hepatocellular CarcinomaSemantic proximity Read ↗

Emerging Signaling Pathways in Hepatocellular CarcinomaSemantic proximity Read ↗

Unraveling the Molecular Mechanisms Involved in HCV-Induced CarcinogenesisSemantic proximity Read ↗

Hepatocellular Carcinoma: Molecular Pathways and New Therapeutic TargetsSemantic proximity Read ↗

Signaling pathways in hepatocellular carcinoma.Semantic proximity Read ↗

Novel oncogenes and tumor suppressor genes in Hepatocellular Carcinoma: Carcinogenesis, progression, and therapeutic targetsSemantic proximity Read ↗

Genetic Alterations and Oncogenic Pathways in Hepatocellular CarcinomaSemantic proximity Read ↗

Prognostic markers and putative therapeutic targets for hepatocellular carcinomaSemantic proximity Read ↗

Genetic and epigenetic control of molecular alterations in hepatocellular carcinoma.Semantic proximity Read ↗

Targeting Signalling Pathways in Hepatocellular CarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.