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Article

State-dependent variation in the inhibitory effect of [D-Ala2, D-Leu5]-enkephalin on hippocampal serotonin release in ground squirrels.

Life sciences - 1 Jan 1991

Kramarova L I, Lee T F, Cui Y, Wang L C

Abstract excerpt

Accumulated evidence has suggested that increased endogenous opioid activities may facilitate the onset of hibernation either directly or possibly through modulation of other neurotransmitter systems. The seasonal change of [D-Ala2, D-Leu5]-enkephalin (DADLE), a delta receptor agonist, in modulating K+ (35 mM)-induced [3H]-5-hydroxytryptamine (5-HT) release from the hippocampal and hypothalamic slices of...

Topics

Animals
Enkephalin, Leucine-2-Alanine
Female
Genetic Variation
Hibernation
Hippocampus
Hypothalamus
Kinetics
Male
Receptors, Opioid
Sciuridae
Seasons

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Serotonin

Source

Identifiers

PMID: 1847226
DOI: 10.1016/0024-3205(91)90411-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1847226-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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