Metabolomic studies of human lung carcinoma cell lines using <i>in vitro</i>¹H NMR of whole cells and cellular extracts

Abstract excerpt

We report principal component analysis (PCA) of (1)H NMR spectra recorded for a group of human lung carcinoma cell lines in culture and (1)H NMR analysis of extracts from the same samples. The samples studied were cells of lung tumour origin with different chemotherapy drug resistance patterns. For whole cells, it was found that the statistically significant causes of spectral variation were an increase in the...

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