Article
1H-magnetic resonance spectroscopic observation of cultured malignant cells pharmacologically induced to different phenotypes.
Academic radiology - 1 Sept 1996
Nakai T, Ishima R, Sakahara H, Endo K, Konishi J, Akasaka K
Abstract excerpt
RATIONALE AND OBJECTIVES: We evaluated the 1H nuclear magnetic resonance spectra of malignant cells after the administration of drugs that cause morphologic changes. METHODS: 1H spectra of a human lung adenocarcinoma cell line cultured with interferon gamma, dexamethasone, or sodium butyrate were obtained. The peaks were assigned by two-dimensional homonuclear Hartmann-Hahn spectroscopy spectra of the cells and...
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