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Article

Haplotype-specific expression of the human PDGFRA gene correlates with the risk of glioblastomas.

International journal of cancer - 15 Jul 2008

Toepoel Mascha, Joosten Paul H L J, Knobbe Christiane B, Afink Gijs B, Zotz Rainer B, Steegers-Theunissen Regine P M, Reifenberger Guido, van Zoelen Everardus J J

Abstract excerpt

Aberrant expression of the platelet-derived growth factor alpha-receptor (PDGFRA) gene has been associated with various diseases, including neural tube defects and gliomas. We have previously identified 5 distinct haplotypes for the PDGFRA promoter region, designated H1, H2alpha, H2beta, H2gamma and H2delta. Of these haplotypes H1 and H2alpha are the most common, whereby H1 drives low and H2alpha high...

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Identifiers

PMID: 18464291
DOI: 10.1002/ijc.23432

Genes

PDGFRA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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