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Article

Multiple Reassortment Events in the Evolutionary History of H1N1 Influenza A Virus Since 1918

29 Feb 2008

Abstract excerpt

The H1N1 subtype of influenza A virus has caused substantial morbidity and mortality in humans, first documented in the global pandemic of 1918 and continuing to the present day. Despite this disease burden, the evolutionary history of the A/H1N1 virus is not well understood, particularly whether there is a virological basis for several notable epidemics of unusual severity in the 1940s and 1950s. Using a data...

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PMID: 18463694
DOI: 10.1371/journal.ppat.1000012

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