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Article

Seasonal H3N2 and 2009 Pandemic H1N1 Influenza A Viruses Reassort Efficiently but Produce Attenuated Progeny.

Journal of virology - 1 Sept 2017

Phipps Kara L, Marshall Nicolle, Tao Hui, Danzy Shamika, Onuoha Nina, Steel John, Lowen Anice C

Abstract excerpt

Reassortment of gene segments between coinfecting influenza A viruses (IAVs) facilitates viral diversification and has a significant epidemiological impact on seasonal and pandemic influenza. Since 1977, human IAVs of H1N1 and H3N2 subtypes have cocirculated with relatively few documented cases of reassortment. We evaluated the potential for viruses of the 2009 pandemic H1N1 (pH1N1) and seasonal H3N2 lineages to...

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Identifiers

PMID: 28637755
DOI: 10.1128/JVI.00830-17
PMCID: PMC5553182

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