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Article

Anabolic function of phenylalanine hydroxylase in Caenorhabditis elegans.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Aug 2008

Calvo Ana C, Pey Angel L, Ying Ming, Loer Curtis M, Martinez Aurora

Abstract excerpt

In humans, liver phenylalanine hydroxylase (PAH) has an established catabolic function, and mutations in PAH cause phenylketonuria, a genetic disease characterized by neurological damage, if not treated. To obtain novel evolutionary insights and information on molecular mechanisms operating in phenylketonuria, we investigated PAH in the nematode Caenorhabditis elegans (cePAH), where the enzyme is coded by the...

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PMID: 18460651
DOI: 10.1096/fj.08-108522

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PAH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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