Article
The evolution of bladder cancer genomics: What have we learned and how can we use it?
Urologic oncology - 1 Jul 2018
Audenet François, Attalla Kyrollis, Sfakianos John P
Abstract excerpt
BACKGROUND: With advancements in molecular biology techniques, great progress has been made in the understanding of urothelial carcinoma pathogenesis. OBJECTIVE: To examine the historic description of molecular alterations in bladder cancer and their evolution towards our current comprehension of the biology of the disease. RESULTS: Historically, a two-pathway model was described from histological and cytogenetic...
Topics
- Biomarkers, Tumor
- Genome, Human
- Genomics
- Humans
- Mutation
- Prognosis
- Signal Transduction
- Urinary Bladder Neoplasms
