Article
Regression supports two mechanisms of fork processing in phage T4.
Proceedings of the National Academy of Sciences of the United States of America - 13 May 2008
Long David T, Kreuzer Kenneth N
Abstract excerpt
Replication forks routinely encounter damaged DNA and tightly bound proteins, leading to fork stalling and inactivation. To complete DNA synthesis, it is necessary to remove fork-blocking lesions and reactivate stalled fork structures, which can occur by multiple mechanisms. To study the mechanisms of stalled fork reactivation, we used a model fork intermediate, the origin fork, which is formed during replication...
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