Article
Integration host factor positively regulates virulence gene expression in Vibrio cholerae.
Journal of bacteriology - 1 Jul 2008
Stonehouse Emily, Kovacikova Gabriela, Taylor Ronald K, Skorupski Karen
Abstract excerpt
Virulence gene expression in Vibrio cholerae is dependent upon a complex transcriptional cascade that is influenced by both specific and global regulators in response to environmental stimuli. Here, we report that the global regulator integration host factor (IHF) positively affects virulence gene expression in V. cholerae. Inactivation of ihfA and ihfB, the genes encoding the IHF subunits, decreased the...
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