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Article

Involvement of ERCC1 (rs3212986) and ERCC2 (rs1799793, rs13181) polymorphisms of DNA repair genes in breast cancer occurrence in Burkina Faso.

Molecular genetics & genomic medicine - 1 Apr 2023

Adico Marc Donald Wilfried, Zouré Abdou Azaque, Sombié Herman Karim, Kiendrebeogo Touwendpoulimdé Isabelle, Dabré Soayebo, Amegnona Lanyo Jospin, Bakyono Bélélé Siméon, Traoré Lassina, Ouedraogo Teega-Wendé Clarisse, Ouedraogo Rogomenoma Alice, Zohoncon Théodora M, Yonli Albert Théophane, Bayala Bagora, Bambara Hierrhum Aboubacar, Djigma Florencia W, Simpore Jacques

Abstract excerpt

BACKGROUND: Genetic alterations can result in DNA repair defects, increasing susceptibility to breast cancer. The aim of this study was to evaluate the involvement of two DNA repair genes, ERCC1 (rs3212986, GenBank NC_000073.9) and ERCC2 (rs1799793, rs13181, GenBank: NC_000019.10) in the occurrence of breast cancer in Burkina Faso. METHODS: This case-control study enrolled 128 participants including 64 patients...

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PMID: 36594475
DOI: 10.1002/mgg3.2134
PMCID: PMC10094077

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