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Article

Two Unique Novel Prostate-Specific and Androgen-Regulated Fusion Partners of <i>ETV4</i> in Prostate Cancer

1 May 2008

Abstract excerpt

Recently, fusion of ERG to the androgen-regulated, prostate-specific TMPRSS2 gene has been identified as the most frequent genetic alteration in prostate cancer. At low frequency, TMPRSS2-ETV1 and TMPRSS2-ETV4 fusion genes have been described. In this study, we report two novel ETV4 fusion genes in prostate cancer: KLK2-ETV4 and CANT1-ETV4. Both gene fusions have important unique aspects. KLK2 is a...

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PMID: 18451133
DOI: 10.1158/0008-5472.can-08-0198

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Two Unique Novel Prostate-Specific and Androgen-Regulated Fusion Partners of <i>ETV4</i> in Prostate CancerPMID 18451133Read ↗

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