Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A potentially functional polymorphism in the regulatory region of let-7a-2 is associated with an increased risk for diabetic nephropathy.

Gene - 25 Sept 2013

Zhou Ji, Peng Rui, Li Tianju, Luo Xiaomei, Peng Huimin, Zha He, Yin Pin, Wen Li, Zhang Zheng

Abstract excerpt

Diabetic nephropathy (DN) is a major diabetic complication. However, the initiating molecular events triggering DN are unknown. MicroRNAs (miRNAs) have recently been identified as regulators that modulate the target gene expression and are involved in DN. However, the evidence of the mechanism is still insufficient in human samples. In this study, microRNA microarray assay was used to study gene differential...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Diabetic Nephropathies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Primers

Share to MicroRNAs

Share to Oligonucleotide Array Sequence Analysis

Share to Polymorphism, Single Nucleotide

Share to Real-Time Polymerase Chain Reaction

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Identifiers

PMID: 23860321
DOI: 10.1016/j.gene.2013.06.088

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A potentially functional polymorphism in the regulatory region of let-7a-2 is associated with an increased risk for diabetic nephropathy.PMID 23860321Read ↗

MicroRNAs as Regulators of Immune and Inflammatory Responses: Potential Therapeutic Targets in Diabetic NephropathySemantic proximity Read ↗

Association of the Transcription Factor 7 Like 2 (TCF7L2) Polymorphism With Diabetic Nephropathy Risk: A Meta-Analysis.Semantic proximity Read ↗

Emerging roles for miRNAs in the development, diagnosis, and treatment of diabetic nephropathy.Semantic proximity Read ↗

The circulating exosomal microRNAs related to albuminuria in patients with diabetic nephropathySemantic proximity Read ↗

Genetic variations associated with diabetic nephropathy and type II diabetes in a Japanese population.Semantic proximity Read ↗

Expression Profiling and Clinical Significance of Plasma MicroRNAs in Diabetic NephropathySemantic proximity Read ↗

MicroRNA-21 as an early marker of nephropathy in patients with type 1 diabetesSemantic proximity Read ↗

MicroRNAs and Risk Factors for Diabetic Nephropathy in Egyptian Children and Adolescents with Type 1 DiabetesSemantic proximity Read ↗

MicroRNAs in Podocyte Injury in Diabetic NephropathySemantic proximity Read ↗

Association of the Transcription Factor 7-Like 2 (TCF7L2) rs7903146 Polymorphism with the Risk of Diabetic Nephropathy: A Meta-Analysis.Semantic proximity Read ↗

TCF7L2 rs7903146 polymorphism and diabetic nephropathy association is not independent of type 2 diabetes--a study in a south Indian population and meta-analysis.Semantic proximity Read ↗

Association Between miR-30a/SNAI1 Gene Polymorphisms and the Risk of Diabetic Kidney DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.