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Article

Role of the major capsid protein in herpes simplex virus type-1 capsid assembly.

Acta virologica - 1 Dec 1990

Celluzzi C N, Farber F E

Abstract excerpt

Two herpes simplex virus type 1 (HSV-1) temperature-sensitive (ts) mutants with defects in the gene for the major capsid protein, ICP5, were examined for their effects on virion capsid assembly. Polyacrylamide gel electrophoresis revealed that both mutants were able to synthesize wild-type (WT) levels of ICP5 at the nonpermissive temperature. However, the 53 kD capsid protein disappeared concomitant with the...

Topics

Animals
Capsid
Capsid Proteins
Chlorocebus aethiops
DNA, Viral
Fluorescent Antibody Technique
Genes, Viral
Herpes Simplex
Molecular Weight
Mutation
Simplexvirus
Temperature

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Vero Cells

Virion

Virus Replication

Source

Identifiers

PMID: 1983175

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1983175-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Role of the major capsid protein in herpes simplex virus type-1 capsid assembly.PMID 1983175Read ↗

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