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Article

Ab initio and QM/MM study of electron addition on the disulfide bond in thioredoxin.

The journal of physical chemistry. B - 8 May 2008

Rickard Gail A, Bergès Jacqueline, Houèe-Levin Chantal, Rauk Arvi

Abstract excerpt

Thioredoxin controls the intracellular redox potential through a disulfide/dithiol couple. Under conditions of oxidative stress, this protein functions via one-electron exchange, in which formation of the disulfide radical anion occurs. Combined quantum mechanical (QM) and molecular mechanical (M...

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PMID: 18447348
DOI: 10.1021/jp710917t

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18447348-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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