Article
The molecular determinants of the increased reduction potential of the rubredoxin domain of rubrerythrin relative to rubredoxin.
Biophysical journal - 17 Feb 2010
Luo Yan, Ergenekan Can E, Fischer Justin T, Tan Ming-Liang, Ichiye Toshiko
Abstract excerpt
Based on the crystal structures, three possible sequence determinants have been suggested as the cause of a 285 mV increase in reduction potential of the rubredoxin domain of rubrerythrin over rubredoxin by modulating the polar environment around the redox site. Here, electrostatic calculations of crystal structures of rubredoxin and rubrerythrin and molecular dynamics simulations of rubredoxin wild-type and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.