Article
Nitric oxide dioxygenase: an enzymic function for flavohemoglobin.
Proceedings of the National Academy of Sciences of the United States of America - 1 Sept 1998
Gardner P R, Gardner A M, Martin L A, Salzman A L
Abstract excerpt
Nitric oxide (NO*) is a toxin, and various life forms appear to have evolved strategies for its detoxification. NO*-resistant mutants of Escherichia coli were isolated that rapidly consumed NO*. An NO*-converting activity was reconstituted in extracts that required NADPH, FAD, and O2, was cyanide-sensitive, and produced NO3-. This nitric oxide dioxygenase (NOD) contained 19 of 20 N-terminal amino acids identical...
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