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Article

Mutations in human monoamine-related neurotransmitter pathway genes.

Human mutation - 1 Jul 2008

Haavik Jan, Blau Nenad, Thöny Beat

Abstract excerpt

Biosynthesis and metabolism of serotonin and catecholamines involve at least eight individual enzymes that are mainly expressed in tissues derived from the neuroectoderm, e.g., the central nervous system (CNS), pineal gland, adrenal medulla, enterochromaffin tissue, sympathetic nerves, and ganglia. Some of the enzymes appear to have additional biological functions and are also expressed in the heart and various...

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Source

Identifiers

PMID: 18444257
DOI: 10.1002/humu.20700

Genes

COMT
PNMT
TPH1
TPH2
DBH
DDC
MAOA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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