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Article

Cardiac differentiation in Xenopus requires the cyclin-dependent kinase inhibitor, p27Xic1.

Cardiovascular research - 1 Aug 2008

Movassagh Mehregan, Philpott Anna

Abstract excerpt

AIMS: Cyclin-dependent kinase inhibitors (CDKIs) play a critical role in negatively regulating the proliferation of cardiomyocytes, although their role in cardiac differentiation remains largely undetermined. We have shown that the most prominent CDKI in Xenopus, p27(Xic1)(Xic1), plays a role in...

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Identifiers

PMID: 18442987
DOI: 10.1093/cvr/cvn105
PMCID: PMC2492727

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18442987-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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