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Article

IS1096-mediated DNA rearrangements play a key role in genome evolution of Mycobacterium smegmatis.

Tuberculosis (Edinburgh, Scotland) - 1 Sept 2008

Wang Xiao-Ming, Galamba Alexandra, Warner Digby F, Soetaert Karine, Merkel Jane S, Kalai Michael, Bifani Pablo, Lefèvre Philippe, Mizrahi Valerie, Content Jean

Abstract excerpt

The acquisition of DNA and the loss of genetic information are two important mechanisms that contribute to strain-specific differences in genome content. In this study, comparative genomics has allowed us to infer the roles of genomic rearrangement and changes in both distribution and copy number of the insertion element, IS1096, in the evolution of Mycobacterium smegmatis mc2155 from its progenitor, M. smegmatis...

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Share to DNA, Bacterial
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18439874
DOI: 10.1016/j.tube.2008.02.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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