Article
Association between fatty acid binding protein 3 gene variants and essential hypertension in humans.
American journal of hypertension - 1 Jun 2008
Ueno Takahiro, Soma Masayoshi, Tabara Yasuharu, Tokunaga Katsushi, Tahira Kzunobu, Fukuda Noboru, Matsumoto Koichi, Nakayama Tomohiro, Katsuya Tomohiro, Ogihara Toshio, Makita Yoshio, Hata Akira, Yamada Michiko, Takahashi Norio, Hirawa Nobuhito, Umemura Satoshi, Miki Tetsuro
Abstract excerpt
BACKGROUND: We have earlier identified a quantitative trait locus (QTL) on rat chromosome 5 that appears to be primarily under the control of the sympathetic nervous system. Because sympathetic overactivity is related to both hypertension and insulin resistance, FABP3 is a candidate gene for the link between this QTL and blood pressure regulation. In this study, therefore, we explored the role of FABP3 genetic...
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