Article
Genetics of drug-resistant Plasmodium falciparum malaria in the Venezuelan state of Bolivar.
The American journal of tropical medicine and hygiene - 1 Oct 2002
Contreras Carmen E, Cortese Joseph F, Caraballo Alejandro, Plowe Christopher V
Abstract excerpt
The state of Bolivar in Venezuela experiences episodic outbreaks of multidrug-resistant Plasmodium falciparum malaria. We obtained P. falciparum-infected blood samples in Bolivar in 1998-2000, and performed molecular assays for mutations conferring resistance to the antifolate combination of sulf...
Topics
- Alleles
- Animals
- Dihydropteroate Synthase
- Drug Resistance
- Humans
- Malaria, Falciparum
- Membrane Proteins
- Membrane Transport Proteins
- Plasmodium falciparum
- Protozoan Proteins
- Tetrahydrofolate Dehydrogenase
- Venezuela
