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Article

Yeast Pgc1p (YPL206c) controls the amount of phosphatidylglycerol via a phospholipase C-type degradation mechanism.

The Journal of biological chemistry - 20 Jun 2008

Simocková Mária, Holic Roman, Tahotná Dana, Patton-Vogt Jana, Griac Peter

Abstract excerpt

The product of the open reading frame YPL206c, Pgc1p, of the yeast Saccharomyces cerevisiae displays homology to bacterial and mammalian glycerophosphodiester phosphodiesterases. Deletion of PGC1 causes an accumulation of the anionic phospholipid, phosphatidylglycerol (PG), especially under conditions of inositol limitation. This PG accumulation was not caused by increased production of phosphatidyl-glycerol...

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Source

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Identifiers

PMID: 18434318
DOI: 10.1074/jbc.M800868200
PMCID: PMC2427352

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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