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Article

Wnt signalling and its impact on development and cancer.

Nature reviews. Cancer - 1 May 2008

Klaus Alexandra, Birchmeier Walter

Abstract excerpt

The Wnt signalling pathway is an ancient system that has been highly conserved during evolution. It has a crucial role in the embryonic development of all animal species, in the regeneration of tissues in adult organisms and in many other processes. Mutations or deregulated expression of components of the Wnt pathway can induce disease, most importantly cancer. The first gene to be identified that encodes a Wnt...

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PMID: 18432252
DOI: 10.1038/nrc2389

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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