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Article

Endothelial nitric oxide synthase intron 4a/b polymorphism and early atherosclerotic changes in hypopituitary GH-deficient adult patients.

European journal of endocrinology - 1 May 2008

Sen Fatma, Demirturk Mustafa, Abaci Neslihan, Golcuk Ebru, Oflaz Huseyin, Elitok Ali, Kutluturk Faruk, Issever Halim, Unaltuna Nihan Erginel, Ozbey Nese Colak

Abstract excerpt

OBJECTIVE: Endothelial nitric oxide synthase (eNOS) intron 4a/b polymorphism is associated with plasma NO concentrations and coronary artery disease/hypertension in various populations. GH deficiency in adulthood predisposes to reduced NO concentrations and premature atherosclerosis. Our aim was to determine whether intron 4a/b polymorphism of eNOS gene influences endothelial function and early atherosclerotic...

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Source

Identifiers

PMID: 18426819
DOI: 10.1530/EJE-07-0704

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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