Article
Prevention of atherosclerosis in LDL receptor-mutant mice by human umbilical cord blood cells.
Research communications in molecular pathology and pharmacology - 1 Jan 2005
Ende Norman, Ende Milton, Chen Ruifeng, Coakley Kathleen, Reddi Alluru S
Abstract excerpt
Previous studies have shown that congenic bone marrow transplantation into apolipoprotein E-deficient mice prevented hypercholesterolemia and atherosclerosis. In this study, we examined the effect of intravenous administration of human umbilical cord blood (HUCB) mononuclear cells on the progression of atherosclerosis in male homozygous mice that had mutation in the low-density lipoprotein receptor (Ldlr(tm1Her)...
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