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Article

Interleukin-12B gene polymorphism frequencies in Egyptians and sex-related susceptibility to hepatitis C infection.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Aug 2013

Youssef Samar Samir, Mostafa Asmaa, Nasr Amal Soliman, el Zanaty Taher, Seif Sameh Mohamed

Abstract excerpt

Hepatitis C virus (HCV) infection is a major health problem worldwide. Egypt is the country with the highest HCV infection epidemic in the world. Interleukin (IL)-12 is a cytokine that has been shown to have a potent role as an antiviral cytokine. IL-12 is a heterodimer of the polypeptides p35 and p40. IL-12 B, the gene encoding IL-12 p40, is polymorphic, and a functional single-nucleotide polymorphism (SNP) of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23600862
DOI: 10.1089/jir.2012.0161

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