Article
Pharmacogenetics: potential role in the treatment of diabetes and obesity.
Expert opinion on pharmacotherapy - 1 May 2008
Vella Adrian, Camilleri Michael
Abstract excerpt
BACKGROUND: Common genetic variation is associated with increased risk of common metabolic diseases such as type 1 and type 2 diabetes, and obesity. Increasing experience with genetic association studies has led to an understanding of the large sample sizes required to detect a weak to moderate genetic predisposition to disease, the need to reproduce such associations in independent cohorts, and the statistical...
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