Article
Pharmacogenetics and target identification in diabetes.
Current opinion in genetics & development - 1 Jun 2018
Pearson Ewan R
Abstract excerpt
In diabetes, pharmacogenetics can be used both to identify patient subgroups who will have most benefit and/or least harm from a particularly treatment, and to gain insights into the molecular mechanisms of drug action and disease aetiology. There is increasing evidence that genetic variation alters response to diabetes treatments-both in terms of glycaemic response and side effects. This can be seen with...
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