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Article

Pyruvate kinase deficiency and malaria.

The New England journal of medicine - 24 Apr 2008

Ayi Kodjo, Min-Oo Gundula, Serghides Lena, Crockett Maryanne, Kirby-Allen Melanie, Quirt Ian, Gros Philippe, Kain Kevin C

Abstract excerpt

Malaria that is caused by Plasmodium falciparum is a significant global health problem. Genetic characteristics of the host influence the severity of disease and the ultimate outcome of infection, and there is evidence of coevolution of the plasmodium parasite with its host. In humans, pyruvate kinase deficiency is the second most common erythrocyte enzyme disorder. Here, we show that pyruvate kinase deficiency...

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Share to Erythrocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18420493
DOI: 10.1056/NEJMoa072464

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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