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Article

Sequence analysis of filaggrin gene by novel shotgun method in Japanese atopic dermatitis.

Journal of dermatological science - 1 Aug 2008

Sasaki Takashi, Kudoh Jun, Ebihara Tamotsu, Shiohama Aiko, Asakawa Shuichi, Shimizu Atsushi, Takayanagi Atsushi, Dekio Itaru, Sadahira Chieko, Amagai Masayuki, Shimizu Nobuyoshi

Abstract excerpt

BACKGROUND: Recent reports indicated that nonsense mutations in filaggrin (FLG) found in ichthyosis vulgaris (IV) patients are predisposing factors for atopic dermatitis (AD) with asthma. The exon 3 of FLG contains tandemly repeated, highly homologous, 11-13 sequence units of 972 or 975 bp, each of which corresponds to the coding sequence of the processed filaggrin with slight sequence difference. This unique...

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Source

Identifiers

PMID: 18420385
DOI: 10.1016/j.jdermsci.2008.02.009

Genes

FLG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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