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Article

Specific filaggrin mutations cause ichthyosis vulgaris and are significantly associated with atopic dermatitis in Japan.

The Journal of investigative dermatology - 1 Jun 2008

Nomura Toshifumi, Akiyama Masashi, Sandilands Aileen, Nemoto-Hasebe Ikue, Sakai Kaori, Nagasaki Akari, Ota Mitsuhito, Hata Hiroo, Evans Alan T, Palmer Colin N A, Shimizu Hiroshi, McLean W H Irwin

Abstract excerpt

Mutations in the gene encoding filaggrin (FLG) have been identified as the cause of ichthyosis vulgaris (IV) and shown to be major predisposing factors for atopic dermatitis (AD). However, these studies have been mainly carried out in European populations. In early 2007, we identified two Orienta...

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Identifiers

PMID: 18200065
DOI: 10.1038/sj.jid.5701205

Genes

FLG

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18200065-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Specific filaggrin mutations cause ichthyosis vulgaris and are significantly associated with atopic dermatitis in Japan.PMID 18200065Read ↗

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